In this book, the author, a physician and writer employs his wide-ranging and interdisciplinary approach to science and medicine, explaining how art, history, superheroes, sex workers, and sports stars all help us understand the impact of our lives on our genes, and our genes on our lives. He explains new concepts in human genetics and health that indicate that the fundamental nature of the human genome is much more fluid and flexible than originally thought. He reveals how genetic breakthroughs are completely transforming our understanding of both the world and our lives. Conventional wisdom dictates that our genetic destiny is fixed at conception. But this book shows us that the human genome is far more fluid and fascinating than your ninth grade biology teacher ever imagined. By bringing us to the bedside of his unique and complex patients, he demonstrates what rare genetic conditions can teach us all about our own health and well-being. In the brave new world we are rapidly rocketing into, genetic knowledge has become absolutely crucial. This book provides a roadmap for this journey by teaching: Why you may have recovered from the psychological trauma caused by childhood bullying, but your genes may remain scarred for life ; How fructose is the sugar that makes fruits sweet, but if you have certain genes, consuming it can buy you a one-way trip to the coroner's office ; Why ingesting common painkillers is like dosing yourself repeatedly with morphine, if you have a certain set of genes ; How insurance companies legally use your genetic data to predict the risk of disability for you and your children, and how that impacts the coverage decisions they make for your family ; How to have the single most important conversation with your doctor, one that can save your life ; And finally, Why people with rare genetic conditions hold the keys to medical problems affecting millions. This book will alter how you view your genes, your health, and your life.

Everything is about to change -- How geneticists think -- When genes misbehave: what Apple, Costco, and a Danish sperm donor teach us about genetic expression -- Changing our genes: how trauma, bullying, and royal jelly alter our genetic destiny -- Use it or lose it: how our lives and genes conspire to make and break our bones -- Feed your genes: what our ancestors, vegans, and our microbiomes teach us about nutrition -- Genetic dosing: how deadly painkillers, the prevention paradox, and Ötzi the iceman are changing the face of medicine -- Picking sides: how genes help us decide between left and right -- We're all X-men: what Sherpas, sword swallowers, and genetically doped athletes teach us about ourselves -- Hacking your genome: why big tobacco, insurance companies, your doctor, and even your lover all want to decode your DNA -- Mail-order child: the unintended consequences of submarines, sonar, and duplicated genes -- Putting it all together: what rare diseases teach us about our genetic inheritance -- One last thing.