Thanks to major advances in big data technologies and precision medicine, healthcare is now becoming the new frontier for both scientific research and economic development. This volume covers a range of aspects, including: big data management for healthcare; physiological and gut microbiota û data collection and analysis; big data standardization and ontology; and personal data privacy and systems level modeling in the healthcare context. The book offers a valuable resource for biomedical informaticians, clinicians, health practitioners and researchers alike.

How to become a smart patient in the era of precision medicine -- Physiological informatics: collection and analyses of data from wearable sensors and smartphone for healthcare -- Entropy for the complexity of physiological signal dynamics -- Data platform for the research and preventionof Alzheimer's Disease -- Data analysis for gut microbiota and health -- Ontology-based vaccine adverse event representation and analysis -- LEMRG: decision rule generation algorithm for mining MicroRNA expression data -- Privacy challenges of genomic big data -- System health: a transition from disease management toward health promotion.